Hyaluronic acid has become a staple of facial skincare. Naturally present in the skin, it plays an essential role in hydration, firmness and skin suppleness. But not all hyaluronic acids are created equal.
Advances in biotechnology and skin neuroscience have made it possible to develop biomimetic forms, capable of mimicking the skin's natural behaviour for deeper, longer-lasting hydration.
Discover what hyaluronic acid does, its benefits, the different forms available today and how to integrate it effectively into your routine.
What is hyaluronic acid?
Hyaluronic acid is a molecule found throughout the body, particularly in the skin, joints and connective tissues. Nearly 50% of the body's hyaluronic acid is concentrated in the skin.
A true hydration reservoir, it can hold up to 1,000 times its weight in water. In the dermis, it helps maintain the skin's hydration while contributing to its suppleness, firmness and elasticity.
Contrary to popular belief, hyaluronic acid is continuously renewed by the body. With age, but also under the effect of oxidative stress, pollution or UV exposure, its production gradually declines while its breakdown accelerates.
As a guide, it is estimated that by around age 50, the amount of hyaluronic acid naturally present in the skin has decreased by roughly 50%.
The skin then becomes more prone to dehydration, the first fine lines, tightness and loss of radiance.

Hyaluronic acid: what are its benefits for the skin?
Thanks to its exceptional ability to attract and retain water within the tissues, hyaluronic acid is now considered one of the reference actives for skin hydration.
Its benefits, however, go well beyond simply supplying water — they also extend to the skin's comfort, suppleness and overall appearance.
Maintaining skin hydration
Thanks to its powerful humectant properties, hyaluronic acid helps capture moisture and hold it within the upper layers of the epidermis.
Reducing feelings of tightness
When the skin lacks water, it can become uncomfortable and more sensitive or reactive to temperature changes, wind or certain cosmetic products.
By helping to maintain hydration, hyaluronic acid helps limit the feelings of tightness often associated with skin dehydration.
Improving the skin's suppleness and plumpness
Properly hydrated skin is generally softer, more supple and more pleasant to the touch.
Hyaluronic acid helps preserve this natural elasticity.
Smoothing dehydration lines
Some fine lines are directly linked to a lack of water in the skin's upper layers.
Hyaluronic acid helps visibly smooth these dehydration lines.
Supporting the skin's barrier function
Well-hydrated skin generally performs its protective role against external aggressors more effectively.
Preserving the complexion's radiance
When the skin is dehydrated, it can quickly appear duller and more tired.
Better hydration helps restore a brighter, more even and visibly fresher complexion.
Beyond its hydrating action, hyaluronic acid works on several essential dimensions of the skin: comfort, suppleness, radiance and the preservation of its natural balance. It is this versatility that makes it one of the most widely used actives in modern dermo-cosmetic skincare.

Are all hyaluronic acids the same?
Not exactly.
The term "hyaluronic acid" covers different forms whose properties vary according to their molecular weight. Some act mainly on the skin's surface, while others contribute to longer-lasting hydration.
Understanding these differences helps you choose your skincare according to your skin's needs.
High-molecular-weight hyaluronic acid
Mainly active on the skin's surface, high-molecular-weight hyaluronic acid helps limit water evaporation and delivers an immediate plumping effect.
Choose it if your skin occasionally lacks comfort, feels tight or looks dull.
Low-molecular-weight hyaluronic acid
Thanks to its smaller size, low-molecular-weight hyaluronic acid penetrates further into the skin's upper layers.
Its action works over time and helps preserve the skin's suppleness.
Particularly valuable for recurrently dehydrated skin or skin prone to the first fine lines.
How do you know which type of hyaluronic acid a product contains?
For consumers, this is often difficult to determine.
Brands rarely communicate the molecular weight used, and the simple mention of "hyaluronic acid" on the packaging reveals nothing about its form or how it works.
That is why the most advanced formulas generally combine several types of hyaluronic acid in order to act at different levels of the skin.
Biomimetic hyaluronic acid: a new generation inspired by the skin
Advances in biotechnology and skin neuroscience have made it possible to go beyond the simple distinction between high and low molecular weight, with the development of mimetic hyaluronic acid.
The idea? Not merely hydrating the surface, but "speaking" to the skin's cells.
Biomimetic hyaluronic acid:
- replicates the structure of the hyaluronic acid naturally present in the skin
- improves cellular communication
- optimises water retention
- strengthens the skin barrier
- delivers smarter, longer-lasting hydration
Some Swiss-made formulas combine several molecular weights of hyaluronic acid with biomimetic actives derived from biotechnology.
Céline's advice
When choosing a hyaluronic acid skincare product, don't stop at the mere presence of the ingredient on the label.
The difference lies in the quality of the formula, the combination of several forms of hyaluronic acid and the presence of complementary actives capable of sustainably supporting the skin's hydration and comfort.
This is precisely the approach behind the C-Derma Face Serum, which combines a duo of biomimetic hyaluronic acid with several soothing and protective actives such as CBD, green tea and chamomile.
Developed according to a Swiss dermo-scientific approach, its formula works simultaneously on hydration, skin comfort and skin-barrier support.
To maximise the benefits, favour these "multi-molecular" formulas capable of acting at different levels of the skin: on the surface to improve immediate comfort and radiance, but also in the deeper upper layers to durably preserve the skin's hydration and suppleness.
Which skin types is hyaluronic acid suited to?
One of the main strengths of hyaluronic acid is its versatility. Thanks to its excellent tolerance, it can be integrated into most skincare routines.
It is particularly valuable for:
- Dehydrated skin, which lacks water and experiences feelings of tightness or discomfort.
- Dry skin, as a complement to nourishing skincare designed to strengthen the skin barrier.
- Sensitive skin or skin prone to redness, which often needs a better water balance to preserve its comfort.
- Combination to oily skin, because it hydrates without clogging pores or leaving a greasy film.
- Mature skin, as it perfectly complements an anti-ageing routine by restoring volume.
- Younger skin, especially when prone to dehydration, excess sebum or blemishes linked to the use of drying products.
Hyaluronic acid is therefore suitable for the vast majority of skin types. Note: even oily skin can be dehydrated. Hyaluronic acid hydrates precisely without adding oil.
How to use hyaluronic acid in a facial routine?
To enjoy the full benefits of hyaluronic acid, integrate it into a coherent routine.
Step 1: cleanse the skin gently
Hyaluronic acid is ideally applied to clean skin.
A gentle cleanse removes impurities while preserving the skin barrier. Conversely, an overly harsh cleanser can heighten feelings of tightness.
Step 2: apply a hyaluronic acid serum
A hyaluronic acid serum is generally the form most concentrated in actives.
To optimise its effectiveness, apply it right after cleansing on slightly damp skin. The presence of water enhances its action.
Step 3: apply a moisturiser
A suitable moisturiser helps lock in the water delivered to the skin and limit its evaporation.
The C-Derma Day and Night Creams complete the serum's action thanks to a combination of biomimetic actives and plant oils that help maintain the skin's hydration and suppleness.
Step 4: protect the skin with SPF
Exposure to UVA and UVB rays tends to accelerate skin ageing and contributes to the gradual breakdown of the hyaluronic acid naturally present in the skin.
Applying a sunscreen daily helps preserve the skin's moisture reserves and limit the visible effects of photoageing.
Conclusion: an essential active for hydration
If hyaluronic acid has become a staple of facial skincare, it is no coincidence. Naturally present in the skin, it contributes to its hydration, suppleness and everyday comfort.
Its value is not limited to mature skin or anti-ageing routines. Young, dry, dehydrated, sensitive or combination skin can benefit too, provided you choose a formula suited to its needs.
Beyond the active itself, it is now the intelligence of the formula that makes the difference: a combination of several molecular weights, biomimetic actives and ingredients capable of supporting the skin barrier. A more modern vision of hydration — one that seeks less to correct the skin than to support it over time.
FAQ - Hyaluronic acid and its benefits
What does hyaluronic acid do for the skin?
Hyaluronic acid helps hold water within the skin, which contributes to preserving its comfort, suppleness and elasticity. It is particularly appreciated for its action on feelings of tightness, dehydration lines and lack of radiance.
Can hyaluronic acid be used every day?
Yes. Hyaluronic acid is generally well tolerated and can be used daily, morning and evening. For best results, it is often recommended to apply it as a serum before a suitable moisturiser.
Is hyaluronic acid suitable for oily skin?
Yes. Contrary to popular belief, oily skin can also lack water. Hyaluronic acid hydrates the skin without a greasy effect and without clogging pores, making it an active particularly well suited to combination and oily skin.
At what age should you use hyaluronic acid?
There is no specific age. Hyaluronic acid can be used whenever the skin needs hydration. It is therefore suitable for teenage skin as well as mature skin.
Is hyaluronic acid suitable for sensitive skin?
Yes. Thanks to its excellent affinity with the skin, hyaluronic acid is generally well tolerated by sensitive skin. It helps improve skin comfort and can help limit the feelings of discomfort linked to dehydration.
Hyaluronic acid: serum or cream?
The two are complementary. The serum delivers a higher concentration of hydrating actives, while the cream helps maintain hydration and limit water loss throughout the day.
At C-Derma, the Face Serum combines a duo of biomimetic hyaluronic acid with soothing actives such as CBD, green tea and chamomile. The Day and Night Creams complete this action thanks to a combination of biomimetic actives and plant oils that durably strengthen the skin's hydration.
To understand how to integrate them into your routine, read our article "How to hydrate facial skin effectively".









